Nras^em8Burd
Endonuclease-mediated Allele Detail

Summary

• Symbol: Nras^em8Burd
• Name: neuroblastoma ras oncogene; endonuclease-mediated mutation 8, Christin Burd
• MGI ID: MGI:6850616
• Synonyms: LSL-NrasG13D, Nras^{em8(G13D)Burd}
• Gene: Nras Location: Chr3:102965643-102975230 bp, + strand Genetic Position: Chr3, 45.25 cM
• Alliance: Nras^em8Burd page

Mutation origin

• Strain of Origin: B6.Cg-Tg(Tyr-cre/ERT2)13Bos Nras^em5Burd/Mmnc

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutations: Insertion, Single point mutation
• Mutation details: CRISPR-targeting produced the amino acid substitution of glycine to aspartic acid at position 13 (G13D). A floxed stop cassette in intron 1 prevents expression unless removed by cre-mediated recombination. (J:94077)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nras Mutation: 44 strains or lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 2 reference(s)