Nrasem7Burd
Endonuclease-mediated Allele Detail
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Symbol: |
Nrasem7Burd |
Name: |
neuroblastoma ras oncogene; endonuclease-mediated mutation 7, Christin Burd |
MGI ID: |
MGI:6850615 |
Synonyms: |
LSL-NrasG12D, Nrasem7(G12D)Burd |
Gene: |
Nras Location: Chr3:102965643-102975230 bp, + strand Genetic Position: Chr3, 45.25 cM
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Alliance: |
Nrasem7Burd page
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Allele Type: |
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Endonuclease-mediated (Conditional ready) |
Mutations: |
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Insertion, Single point mutation
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Mutation details: CRISPR-targeting produced the amino acid substitution of glycine to aspartic acid at position 13 (G12D). A floxed stop cassette in intron 1 prevents expression unless removed by cre-mediated recombination. A silent G to A mutation occurred in the third nucleotide of codon 15.
(J:94077, J:325350)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Nras Mutation: |
44 strains or lines available
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Original: |
J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015; |
All: |
2 reference(s) |
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