Tg(Gata1-cre/ERT2)L245Jeng
Transgene Detail
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Symbol: |
Tg(Gata1-cre/ERT2)L245Jeng |
Name: |
transgene insertion L245, James Douglas Engel |
MGI ID: |
MGI:6850167 |
Synonyms: |
G1BCreERT2 |
Transgene: |
Tg(Gata1-cre/ERT2)L245Jeng Location: unknown
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Alliance: |
Tg(Gata1-cre/ERT2)L245Jeng page
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Transgene Type: |
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Transgenic (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Tg(Gata1-cre/ERT2)L245Jeng expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Gata1 (MGI:95661) |
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Mutation details: A tamoxifen-inducible CreER(T2) fusion gene was introduced to the start codon of the mouse Gata1 gene contained within BAC RP23-443E19. The modified BAC was introduced to C57BL/6J zygotes. Lines L245 and L259 were generated and shared similar profiles of the erythroid lineage-specific cre activities. The line L259 was used for the studies. The insertion site and copy number of the transgene are unknown.
(J:315683)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Gata1
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:315683 Yu L, et al., An erythroid-to-myeloid cell fate conversion is elicited by LSD1 inactivation. Blood. 2021 Nov 4;138(18):1691-1704 |
All: |
1 reference(s) |
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