Gt(ROSA)26Sor^{em1(Eef1a1-IGFBP5)Cfbos}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{em1(Eef1a1-IGFBP5)Cfbos}
• Name: gene trap ROSA 26, Philippe Soriano; endonuclease-mediated mutation 1, Carol Feghali-Bostwick
• MGI ID: MGI:6850022
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{em1(Eef1a1-IGFBP5)Cfbos} page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Inserted expressed sequence)
• Mutation: Insertion
• Gt(ROSA)26Sor^{em1(Eef1a1-IGFBP5)Cfbos} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  IGFBP5 (3488)

  Igfbp5

  (MGI:96440)

• CRISPR-targeting inserted the mouse promoter driving expression of the human sequence. (J:317161, J:317162)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1089 strains or lines available

References

• Original: J:317161 Nguyen XX, et al., Phenotypic Characterization of Transgenic Mice Expressing Human IGFBP-5. Int J Mol Sci. 2020 Dec 30;22(1):335
• All: 2 reference(s)