Rnf187em1(IMPC)J
Endonuclease-mediated Allele Detail
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Symbol: |
Rnf187em1(IMPC)J |
Name: |
ring finger protein 187; endonuclease-mediated mutation 1, Jackson |
MGI ID: |
MGI:6849819 |
Gene: |
Rnf187 Location: Chr11:58823114-58829732 bp, - strand Genetic Position: Chr11, 36.37 cM, cytoband B2
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Alliance: |
Rnf187em1(IMPC)J page
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IMPC: |
Rnf187 gene page |
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Strain of Origin: |
C57BL/6NJ
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Project Collection: |
IMPC
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Allele Type: |
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Endonuclease-mediated (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences AAGTCCTTGGAACCTGGTCA and ATAAGATTACTCATCCTGCA, which resulted in a 6959 bp deletion beginning at Chromosome 11 position 58,823,054 bp and ending after 58,830,012 bp (GRCm39/mm39). This mutation deletes ENSMUSE00000590381, ENSMUSE00000105447, ENSMUSE00000105448 and ENSMUSE00000678141 (exons 1-4) and 5010 bp of flanking intronic sequence including the start site, splice acceptor and donor and is predicted to result in a null allele. There is a 1 bp (T) insertion at the deletion site.
(J:188991)
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Inheritance: |
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Not Specified |
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View phenotypes and curated references for all genotypes (concatenated display).
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Original: |
J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012; |
All: |
3 reference(s) |
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