Zfp82^tm1.2Cya
Targeted Allele Detail

Summary

• Symbol: Zfp82^tm1.2Cya
• Name: zinc finger protein 82; targeted mutation 1.2, Cyagen Biosciences
• MGI ID: MGI:6849766
• Synonyms: Zfp82^tm1.2Cgen, Znf545^delta
• Gene: Zfp82 Location: Chr7:29755459-29772248 bp, - strand Genetic Position: Chr7, 17.26 cM
• Alliance: Zfp82^tm1.2Cya page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:316087
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct inserted into intron 4 an FRT site, engrailed splice acceptor, IRES sequence, EGFP reporter gene, polyadenylation sequence, loxP, FRT site, and loxP site. An additional loxP site was inserted downstream of exon 5. Flp-mediated recombination removed the reporter and selection cassette. Cre-mediated recombination removed exon 5. (J:316087)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zfp82 Mutation: 29 strains or lines available

References

• Original: J:316087 Wang S, et al., ZNF545 loss promotes ribosome biogenesis and protein translation to initiate colorectal tumorigenesis in mice. Oncogene. 2021 Dec;40(48):6590-6600
• All: 1 reference(s)