Prkcd^tm1Shb
Targeted Allele Detail

Summary

• Symbol: Prkcd^tm1Shb
• Name: protein kinase C, delta; targeted mutation 1, Satoru Arata
• MGI ID: MGI:6842314
• Synonyms: Prkcd^f
• Gene: Prkcd Location: Chr14:30317311-30348167 bp, - strand Genetic Position: Chr14, 18.82 cM
• Alliance: Prkcd^tm1Shb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:312555
• Parent Cell Line: RENKA (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting construct inserted a loxP site and PGK-neo cassette upstream of exon 7 and a loxP site downstream of exon 7. (J:312555)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Prkcd Mutation: 52 strains or lines available

References

• Original: J:312555 Ou P, et al., SMS2 deficiency impairs PKCdelta-regulated B cell tolerance in the germinal center. Cell Rep. 2021 Aug 31;36(9):109624
• All: 7 reference(s)