Gpr37^em2Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gpr37^em2Smoc
• Name: G protein-coupled receptor 37; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
• MGI ID: MGI:6840941
• Synonyms: Gpr37^{em1(flox)Smoc}, GPR37^loxP
• Gene: Gpr37 Location: Chr6:25668522-25689979 bp, - strand Genetic Position: Chr6, 11.65 cM
• Alliance: Gpr37^em2Smoc page

Mutation origin

• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting generated a floxed allele. (J:312934)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpr37 Mutation: 35 strains or lines available

References

• Original: J:312934 Qian Z, et al., Osteocalcin attenuates oligodendrocyte differentiation and myelination via GPR37 signaling in the mouse brain. Sci Adv. 2021 Oct 22;7(43):eabi5811
• All: 1 reference(s)