Ngf^tm1.1Mini
Targeted Allele Detail

Summary

• Symbol: Ngf^tm1.1Mini
• Name: nerve growth factor; targeted mutation 1.1, Liliana Minichiello
• MGI ID: MGI:6840222
• Synonyms: NGF^fl
• Gene: Ngf Location: Chr3:102377235-102428329 bp, + strand Genetic Position: Chr3, 45.25 cM
• Alliance: Ngf^tm1.1Mini page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:130626
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting construct inserted upstream of exon 4 a loxP site and downstream of exon 4 a loxP site, IRES sequence, EGFP reporter gene, and FRT-flanked neomycin resistance cassette. Flp-mediated recombination removed the selection cassette. (J:130626)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ngf Mutation: 12 strains or lines available

References

• Original: J:130626 Minichiello L, et al., Mechanism of TrkB-mediated hippocampal long-term potentiation. Neuron. 2002 Sep 26;36(1):121-37
• All: 10 reference(s)