Gdf2^tm1Thbr
Targeted Allele Detail

Summary

• Symbol: Gdf2^tm1Thbr
• Name: growth differentiation factor 2; targeted mutation 1, Thomas Braun
• MGI ID: MGI:6836728
• Gene: Gdf2 Location: Chr14:33662996-33669155 bp, + strand Genetic Position: Chr14, 20.8 cM
• Alliance: Gdf2^tm1Thbr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:316413
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: The targeting vector obtained from EUCOMM inserted upstream of exon 2 an FRT site, lacZ reporter gene, loxP site, neomycin resistance cassette, FRT site, and loxP site. An additional loxP site was inserted downstream, of exon 2. (J:316413)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gdf2 Mutation: 25 strains or lines available

References

• Original: J:316413 Wang L, et al., BMP9 and BMP10 Act Directly on Vascular Smooth Muscle Cells for Generation and Maintenance of the Contractile State. Circulation. 2021 Apr 6;143(14):1394-1410
• All: 1 reference(s)