Thrsp^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Thrsp^em1Cya
• Name: thyroid hormone responsive; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:6834798
• Synonyms: Thrsp^em1Cgen, Thrsp^em1cyagen
• Gene: Thrsp Location: Chr7:97062140-97066757 bp, - strand Genetic Position: Chr7, 53.49 cM, cytoband E3
• Alliance: Thrsp^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Not Specified
• CRISPR-targeting of exon 1 produced a null allele. (J:313716)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Thrsp Mutation: 14 strains or lines available

References

• Original: J:313716 Custodio RJP, et al., Low striatal T3 is implicated in inattention and memory impairment in an ADHD mouse model overexpressing thyroid hormone-responsive protein. Commun Biol. 2021 Sep 20;4(1):1101
• All: 1 reference(s)