Nlrc3^em3Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Nlrc3^em3Smoc
• Name: NLR family, CARD domain containing 3; endonuclease-mediated mutation 3, Shanghai Model Organisms Center
• MGI ID: MGI:6834792
• Gene: Nlrc3 Location: Chr16:3762871-3794496 bp, - strand Genetic Position: Chr16, 2.32 cM
• Alliance: Nlrc3^em3Smoc page

Mutation origin

• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted exons 2 and 3. (J:313999)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Nlrc3 Mutation: 53 strains or lines available

References

• Original: J:313999 Ma R, et al., Nlrc3 Knockout Mice Showed Renal Pathological Changes After HTNV Infection. Front Immunol. 2021;12:692509
• All: 1 reference(s)