Sesn2^em1Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Sesn2^em1Smoc
• Name: sestrin 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:6834774
• Gene: Sesn2 Location: Chr4:132220115-132237767 bp, - strand Genetic Position: Chr4, 65.45 cM
• Alliance: Sesn2^em1Smoc page

Mutation origin

• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted exons 3 through 6. (J:314010)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Sesn2 Mutation: 117 strains or lines available

References

• Original: J:314010 Li JY, et al., Sestrin2 protects dendrite cells against ferroptosis induced by sepsis. Cell Death Dis. 2021 Sep 4;12(9):834
• All: 1 reference(s)