Pdpk1^tm1Zdo
Targeted Allele Detail

Summary

• Symbol: Pdpk1^tm1Zdo
• Name: 3-phosphoinositide dependent protein kinase 1; targeted mutation 1, Zhongjun Dong
• MGI ID: MGI:6834003
• Synonyms: PDK1^flox
• Gene: Pdpk1 Location: Chr17:24292654-24369898 bp, - strand Genetic Position: Chr17, 12.23 cM, cytoband A3.3
• Alliance: Pdpk1^tm1Zdo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:314118
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• The targeting construct generated a floxed allele. (J:314118)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pdpk1 Mutation: 141 strains or lines available

References

• Original: J:314118 Feng P, et al., The kinase PDK1 regulates regulatory T cell survival via controlling redox homeostasis. Theranostics. 2021;11(19):9503-9518
• All: 1 reference(s)