Pou2f3^tm1.1Itl
Targeted Allele Detail

Summary

• Symbol: Pou2f3^tm1.1Itl
• Name: POU domain, class 2, transcription factor 3; targeted mutation 1.1, inGenious Targeting Laboratory
• MGI ID: MGI:6833986
• Synonyms: Pou2f3^fl
• Gene: Pou2f3 Location: Chr9:43035222-43117052 bp, - strand Genetic Position: Chr9, 24.21 cM
• Alliance: Pou2f3^tm1.1Itl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:314313
• Parent Cell Line: iTL BA1 (ES Cell)
• Strain of Origin: (C57BL/6NTac x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting construct floxed exon 5. Flp-mediated recombination removed the FRT-flanked selection cassette. (J:314313)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pou2f3 Mutation: 36 strains or lines available

References

• Original: J:314313 DelGiorno KE, et al., Tuft Cells Inhibit Pancreatic Tumorigenesis in Mice by Producing Prostaglandin D2. Gastroenterology. 2020 Nov;159(5):1866-1881.e8
• All: 1 reference(s)