Pdcd1^em1Arte
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pdcd1^em1Arte
• Name: programmed cell death 1; endonuclease-mediated mutation 1, TaconicArtemis
• MGI ID: MGI:6833888
• Gene: Pdcd1 Location: Chr1:93966027-93980278 bp, - strand Genetic Position: Chr1, 47.47 cM
• Alliance: Pdcd1^em1Arte page

Mutation origin

• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted exons 2 and 3. (J:258822)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pdcd1 Mutation: 47 strains or lines available

References

• Original: J:258822 Hossain DMS, et al., Dinaciclib induces immunogenic cell death and enhances anti-PD1-mediated tumor suppression. J Clin Invest. 2018 Feb 1;128(2):644-654
• All: 4 reference(s)