Ska3^em2Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ska3^em2Cya
• Name: spindle and kinetochore associated complex subunit 3; endonuclease-mediated mutation 2, Cyagen Biosciences
• MGI ID: MGI:6833882
• Gene: Ska3 Location: Chr14:58044018-58063642 bp, - strand Genetic Position: Chr14, 30.51 cM
• Alliance: Ska3^em2Cya page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology deleted exons 2-6. (J:314146)

Expression

In Mice Carrying this Mutation:

5 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ska3 Mutation: 23 strains or lines available

References

• Original: J:314146 Gao W, et al., Targeting SKA3 suppresses the proliferation and chemoresistance of laryngeal squamous cell carcinoma via impairing PLK1-AKT axis-mediated glycolysis. Cell Death Dis. 2020 Oct 26;11(10):919
• All: 1 reference(s)