Smoc1^tm1.1Ytaka
Targeted Allele Detail

Summary

• Symbol: Smoc1^tm1.1Ytaka
• Name: SPARC related modular calcium binding 1; targeted mutation 1.1, Yoshifumi Takahata
• MGI ID: MGI:6833873
• Gene: Smoc1 Location: Chr12:81073582-81233188 bp, + strand Genetic Position: Chr12, 37.28 cM
• Alliance: Smoc1^tm1.1Ytaka page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:314589
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct inserted an FRT-flanked neomycin resistance cassette with a 5' loxP site upstream of exon 1 and an additional loxP site downstream of exon 1. Cre-mediated recombination removed the selection cassette and exon 1. (J:314589)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Smoc1 Mutation: 34 strains or lines available

References

• Original: J:314589 Takahata Y, et al., Smoc1 and Smoc2 regulate bone formation as downstream molecules of Runx2. Commun Biol. 2021 Oct 19;4(1):1199
• All: 1 reference(s)