Ret^{tm6.1(RET/EGFP)Heno}
Targeted Allele Detail

Summary

• Symbol: Ret^{tm6.1(RET/EGFP)Heno}
• Name: ret proto-oncogene; targeted mutation 6.1, Hideki Enomoto
• MGI ID: MGI:6832827
• Gene: Ret Location: Chr6:118128706-118174679 bp, - strand Genetic Position: Chr6, 55.86 cM, cytoband E3-F1
• Alliance: Ret^{tm6.1(RET/EGFP)Heno} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:314923
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Ret^{tm6.1(RET/EGFP)Heno} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  RET (5979)

  Ret	(MGI:97902)

• Mutation details: The targeting construct inserted into the first exon at the translation initiation site a human RET cDNA lacking the stop codon fused with the EGFP reporter, intron/polyadenylation sequence, and floxed neomycin resistance cassette. Cre-mediated recombination removed the selection cassette. (J:314923)

Expression

In Mice Carrying this Mutation:

25 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ret Mutation: 53 strains or lines available

References

• Original: J:314923 Sunardi M, et al., Live visualization of a functional RET-EGFP chimeric receptor in homozygous knock-in mice. Dev Growth Differ. 2021 Aug;63(6):285-294
• All: 1 reference(s)