Cpeb3^tm1.1Kndl
Targeted Allele Detail

Summary

• Symbol: Cpeb3^tm1.1Kndl
• Name: cytoplasmic polyadenylation element binding protein 3; targeted mutation 1.1, Eric R Kandel
• MGI ID: MGI:6832814
• Gene: Cpeb3 Location: Chr19:36998691-37186000 bp, - strand Genetic Position: Chr19, 32.08 cM
• Alliance: Cpeb3^tm1.1Kndl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:223363
• Parent Cell Line: KV1 (ES Cell)
• Strain of Origin: (C57BL/6J x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP (L83) site is placed in intron 1 and an FRT-neomycin-FRT-loxP cassette is placed in intron 2. Flp-mediated recombination removed the FRT-flanked neo cassette leaving exon 3 floxed. (J:223363)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cpeb3 Mutation: 34 strains or lines available

References

• Original: J:223363 Fioriti L, et al., The Persistence of Hippocampal-Based Memory Requires Protein Synthesis Mediated by the Prion-like Protein CPEB3. Neuron. 2015 Jun 17;86(6):1433-48
• All: 1 reference(s)