Cblif^{em1(rtTA)Choie}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cblif^{em1(rtTA)Choie}
• Name: cobalamin binding intrinsic factor; endonuclease-mediated mutation 1, Eunyoung Choi
• MGI ID: MGI:6829633
• Synonyms: GIF-rtTA
• Gene: Cblif Location: Chr19:11724918-11740811 bp, + strand Genetic Position: Chr19, 8.51 cM
• Alliance: Cblif^{em1(rtTA)Choie} page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Transactivator)
• Mutation: Insertion
• CRISPR-targeting introduced the 2A and rtTA sequence at the end of the coding sequence. (J:314964)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cblif Mutation: 30 strains or lines available

References

• Original: J:314964 Caldwell B, et al., Chief cell plasticity is the origin of metaplasia following acute injury in the stomach mucosa. Gut. 2021;:2021-325310
• All: 3 reference(s)