Phf19^tm1Ldc
Targeted Allele Detail

Summary

• Symbol: Phf19^tm1Ldc
• Name: PHD finger protein 19; targeted mutation 1, Luciano Di Croce
• MGI ID: MGI:6827411
• Synonyms: Phf19^fl
• Gene: Phf19 Location: Chr2:34783769-34804038 bp, - strand Genetic Position: Chr2, 23.02 cM, cytoband B
• Alliance: Phf19^tm1Ldc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:313068
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting construct inserted a loxP site upstream of exon 4 and a neomycin resistance cassette with 3' loxP site downstream of exon 5. (J:313068)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Phf19 Mutation: 28 strains or lines available

References

• Original: J:313068 Vizan P, et al., The Polycomb-associated factor PHF19 controls hematopoietic stem cell state and differentiation. Sci Adv. 2020 Aug;6(32):eabb2745
• All: 1 reference(s)