Tg(Prkcd-cre)PIto
Transgene Detail

Summary

• Symbol: Tg(Prkcd-cre)PIto
• Name: transgene insertion P, Shigeyoshi Itohara
• MGI ID: MGI:6827391
• Synonyms: Pkcd-Cre
• Transgene: Tg(Prkcd-cre)PIto Location: unknown
• Alliance: Tg(Prkcd-cre)PIto page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Prkcd-cre)PIto expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Prkcd (MGI:97598)

• Mutation details: Tg construct was created by modifying mouse BAC clone to insert the nuclear localization signal (NLS) Cre-pA cassette and FRT-Amp-FRT sequence into the translational initiation site of the Prkcd gene. The Amp sequence in the obtained BAC construct was removed by flp/FRT recombination in bacteria. Among the multiple lines obtained, a line (P) with high selectivity of recombination in the dorsal thalamic nuclei was selected. (J:254126)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Prkcd (mouse) Summary of all recombinase alleles driven by Prkcd. Alliance mouse Prkcd gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:254126 Zhang Q, et al., Netrin-G1 regulates fear-like and anxiety-like behaviors in dissociable neural circuits. Sci Rep. 2016 Jun 27;6:28750
• All: 2 reference(s)