Usp48^tm1.1Cya
Targeted Allele Detail

Summary

• Symbol: Usp48^tm1.1Cya
• Name: ubiquitin specific peptidase 48; targeted mutation 1.1, Cyagen Biosciences
• MGI ID: MGI:6827188
• Synonyms: USP48^flox, Usp48^tm1.1Cgen
• Gene: Usp48 Location: Chr4:137321079-137385842 bp, + strand Genetic Position: Chr4, 70.0 cM
• Alliance: Usp48^tm1.1Cya page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:307932
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: The targeting vector inserted loxP in the intron upstream of exon 2 of the Usp48 gene and FRT flanked neo cassette and a second loxP site into the intron downstream of exon 2. The neo cassette was removed by flp recombination. (J:307932)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Usp48 Mutation: 218 strains or lines available

References

• Original: J:307932 Du L, et al., USP48 Is Upregulated by Mettl14 to Attenuate Hepatocellular Carcinoma via Regulating SIRT6 Stabilization. Cancer Res. 2021 Jul 15;81(14):3822-3834
• All: 1 reference(s)