Atm^tm1Gct
Targeted Allele Detail

Summary

• Symbol: Atm^tm1Gct
• Name: ataxia telangiectasia mutated; targeted mutation 1, George Tsokos
• MGI ID: MGI:6822320
• Gene: Atm Location: Chr9:53350449-53448040 bp, - strand Genetic Position: Chr9, 29.12 cM, cytoband C-D
• Alliance: Atm^tm1Gct page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:104190
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129T2/SvEms

Mutation description

• Allele Type: Targeted (Not Specified)
• Mutations: Insertion, Nucleotide substitutions
• Mutation details: The targeting construct introduced a neomycin resistance cassette with FRT inserted into intron 51 and a modified exon 51 with the mouse mutation corresponding to the human disease associated mutation T7271G mutation. The resulting amino acid substitution corresponds to the human substitution from valine to glycine (V2424G). (J:104190)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Atm Mutation: 168 strains or lines available

References

• Original: J:104190 The Australian Phenomics Facility at The Australian National University, Heritable mouse mutants from the ENU mutagenesis program at the Australian Phenomics Facility at The Australian National University. MGI Direct Data Submission. 2006-2014
• All: 1 reference(s)