Dbp^em1Drw
Endonuclease-mediated Allele Detail

Summary

• Symbol: Dbp^em1Drw
• Name: D site albumin promoter binding protein; endonuclease-mediated mutation 1, David R Weaver
• MGI ID: MGI:6814682
• Synonyms: Dbp^KI
• Gene: Dbp Location: Chr7:45354658-45359579 bp, + strand Genetic Position: Chr7, 29.45 cM
• Alliance: Dbp^em1Drw page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: CRISPR/Cas9 genome editing is used to replace the stop codon in exon 4 with a T2A-loxP-destabilized GFP (d2EGFP)-pA-loxP-luciferase (Luc2) cassette. (J:314144)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Dbp Mutation: 24 strains or lines available

References

• Original: J:314144 Smith CR, et al., Cell-type specific circadian bioluminescence rjutj,s om Dbp reporter mice. bioRxiv. 2021
• All: 3 reference(s)