Gsdme^em1Jhan
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gsdme^em1Jhan
• Name: gasdermin E; endonuclease-mediated mutation 1, Jiahuai Han
• MGI ID: MGI:6810772
• Synonyms: Gsdme^-
• Gene: Gsdme Location: Chr6:50167013-50240837 bp, - strand Genetic Position: Chr6, 24.13 cM
• Alliance: Gsdme^em1Jhan page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Not Specified
• The null allele was engineered using CRISPR/Cas9 technology. (J:312930)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gsdme Mutation: 43 strains or lines available

References

• Original: J:312930 Zhang P, et al., NLRC4 inflammasome-dependent cell death occurs by a complementary series of three death pathways and determines lethality in mice. Sci Adv. 2021 Oct 22;7(43):eabi9471
• All: 2 reference(s)