Nlrc4^em1Jhan
Endonuclease-mediated Allele Detail

Summary

• Symbol: Nlrc4^em1Jhan
• Name: NLR family, CARD domain containing 4; endonuclease-mediated mutation 1, Jiahuai Han
• MGI ID: MGI:6810770
• Synonyms: Nlrc4^-
• Gene: Nlrc4 Location: Chr17:74733254-74766140 bp, - strand Genetic Position: Chr17, 45.64 cM
• Alliance: Nlrc4^em1Jhan page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Not Specified
• CRISPR-targeting produced a null allele. (J:312930)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nlrc4 Mutation: 72 strains or lines available

References

• Original: J:312930 Zhang P, et al., NLRC4 inflammasome-dependent cell death occurs by a complementary series of three death pathways and determines lethality in mice. Sci Adv. 2021 Oct 22;7(43):eabi9471
• All: 2 reference(s)