Gpa33^{tm1(Ctnnb1*)Ern}
Targeted Allele Detail

Summary

• Symbol: Gpa33^{tm1(Ctnnb1*)Ern}
• Name: glycoprotein A33 transmembrane; targeted mutation 1, Matthias Ernst
• MGI ID: MGI:6806127
• Synonyms: a33^b-neo
• Gene: Gpa33 Location: Chr1:165957807-165994079 bp, + strand Genetic Position: Chr1, 73.49 cM
• Alliance: Gpa33^{tm1(Ctnnb1*)Ern} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:79797
• Parent Cell Line: W9.5/W95 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting construct introduced downstream of the translation stop site a loxP site, IRES, neomycin resistance cassette, polyadenylation sequence, loxP site, IRES sequence, and FLAG-tagged mouse Ctnnb1 cDNA lacking the N-terminal domain amino acids 1-131. (J:79797)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gpa33 Mutation: 139 strains or lines available

References

• Original: J:79797 Orner GA, et al., Response of Apc(min) and A33 (delta N beta-cat) mutant mice to treatment with tea, sulindac, and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). Mutat Res. 2002 Sep 30;506-507:121-7
• All: 1 reference(s)