Sp7tm1(icre)Bcgen
Targeted Allele Detail
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Symbol: |
Sp7tm1(icre)Bcgen |
Name: |
Sp7 transcription factor 7; targeted mutation 1, Biocytogen LLC |
MGI ID: |
MGI:6791387 |
Synonyms: |
Osx-Cre, Sp7tm1(iCre)Bcgen |
Gene: |
Sp7 Location: Chr15:102265038-102275498 bp, - strand Genetic Position: Chr15, 57.51 cM
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Alliance: |
Sp7tm1(icre)Bcgen page
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Germline Transmission: |
Earliest citation of germline transmission:
J:240968
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
C57BL/6
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Allele Type: |
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Targeted (Recombinase) |
Mutation: |
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Insertion
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Sp7tm1(icre)Bcgen expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: An F2A-iCre sequence cassette was placed between the coding sequence of exon 2 and 3UTR of the Sp7 gene in C57BL/6 ES cells.
(J:308681)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Sp7
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Sp7 Mutation: |
21 strains or lines available
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Original: |
J:240968 Liu J, et al., Increased PLEKHO1 within osteoblasts suppresses Smad-dependent BMP signaling to inhibit bone formation during aging. Aging Cell. 2017 Apr;16(2):360-376 |
All: |
5 reference(s) |
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