Krt14tm1(cre/ERT2)Akli
Targeted Allele Detail
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Symbol: |
Krt14tm1(cre/ERT2)Akli |
Name: |
keratin 14; targeted mutation 1, Apostolos Klinakis |
MGI ID: |
MGI:6791378 |
Synonyms: |
Krt14CreERT2 |
Gene: |
Krt14 Location: Chr11:100093988-100098336 bp, - strand Genetic Position: Chr11, 63.43 cM, cytoband D
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Alliance: |
Krt14tm1(cre/ERT2)Akli page
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Germline Transmission: |
Earliest citation of germline transmission:
J:239882
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Parent Cell Line: |
W4 (ES Cell)
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Strain of Origin: |
129S6/SvEvTac
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Allele Type: |
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Targeted (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Krt14tm1(cre/ERT2)Akli expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Krt14 (MGI:96688) |
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Mutation details: A CreERT2-loxP-NeoR-loxP cassette was inserted into Kar14 initiation codon ATG via homologous recombination in ES cells.
(J:239882)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Krt14
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Krt14 Mutation: |
36 strains or lines available
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Original: |
J:239882 Papafotiou G, et al., KRT14 marks a subpopulation of bladder basal cells with pivotal role in regeneration and tumorigenesis. Nat Commun. 2016 Jun 20;7:11914 |
All: |
1 reference(s) |
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