Loxl1^tm1Pctr
Targeted Allele Detail

Summary

• Symbol: Loxl1^tm1Pctr
• Name: lysyl oxidase-like 1; targeted mutation 1, Philip C Trackman
• MGI ID: MGI:6783464
• Gene: Loxl1 Location: Chr9:58195021-58220469 bp, - strand Genetic Position: Chr9, 31.65 cM
• Alliance: Loxl1^tm1Pctr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:311488
• Parent Cell Line: RW-4 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A PGK-neomcyin cassette in the opposite transcriptional orientation replaced and deleted the ATG initiation codon. (J:311488)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Loxl1 Mutation: 37 strains or lines available

References

• Original: J:311488 Alsofi L, et al., Sex-Linked Skeletal Phenotype of Lysyl Oxidase Like-1 Mutant Mice. Calcif Tissue Int. 2016 Feb;98(2):172-85
• All: 1 reference(s)