Cyp2j5^em1Nju
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cyp2j5^em1Nju
• Name: cytochrome P450, family 2, subfamily j, polypeptide 5; endonuclease-mediated mutation 1, Model Animal Research Center of Nanjing University
• MGI ID: MGI:6783421
• Gene: Cyp2j5 Location: Chr4:96517010-96552391 bp, - strand Genetic Position: Chr4, 44.71 cM
• Alliance: Cyp2j5^em1Nju page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted 902 bp. (J:309419)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cyp2j5 Mutation: 29 strains or lines available

References

• Original: J:309419 Kong C, et al., Fusobacterium Nucleatum Promotes the Development of Colorectal Cancer by Activating a Cytochrome P450/Epoxyoctadecenoic Acid Axis via TLR4/Keap1/NRF2 Signaling. Cancer Res. 2021 Sep 1;81(17):4485-4498
• All: 1 reference(s)