Bcam^em1Mtan
Endonuclease-mediated Allele Detail

Summary

• Symbol: Bcam^em1Mtan
• Name: basal cell adhesion molecule; endonuclease-mediated mutation 1, Minoru Tanaka
• MGI ID: MGI:6783420
• Gene: Bcam Location: Chr7:19490063-19504457 bp, - strand Genetic Position: Chr7, 9.94 cM
• Alliance: Bcam^em1Mtan page

Mutation origin

• Strain of Origin: C57BL/6NJcl

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-targeting of exon 1 deleted 11 bp producing a frame shift and premature termination of translation. (J:311901)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bcam Mutation: 35 strains or lines available

References

• Original: J:311901 Miura Y, et al., Differential expression of Lutheran/BCAM regulates biliary tissue remodeling in ductular reaction during liver regeneration. Elife. 2018 Jul 30;7:e36572
• All: 1 reference(s)