Ankfn1^em1Mnw
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ankfn1^em1Mnw
• Name: ankyrin-repeat and fibronectin type III domain containing 1; endonuclease-mediated mutation 1, Mark N Wu
• MGI ID: MGI:6782841
• Synonyms: mWAKE^-
• Gene: Ankfn1 Location: Chr11:89280918-89668727 bp, - strand Genetic Position: Chr11, 54.34 cM
• Alliance: Ankfn1^em1Mnw page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Insertion
• Mutation details: Using CRISPR/Cas9 genome editing, 8 bp base pairs containing a stop codon and generating a downstream frameshift were inserted in exon 4 of the Ankfn1 gene predicted to be in all splice isoforms. (J:312000)

Expression

In Mice Carrying this Mutation:

2 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ankfn1 Mutation: 48 strains or lines available

References

• Original: J:312000 Bell BJ, et al., A clock-driven neural network critical for arousal. bioRxiv. 2020
• All: 1 reference(s)