Gt(ROSA)26Sor^{tm1(CAG-Foxa2)Tesp}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(CAG-Foxa2)Tesp}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Thomas E Spencer
• MGI ID: MGI:6781233
• Synonyms: mFoxa2^LSL
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(CAG-Foxa2)Tesp} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:260511
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence, No functional change)
• Mutation: Insertion
• Mutation details: the targeting construct introduced into the locus a ubiquitously expressing CAG promoter, floxed stop cassette, and the coding sequence for the mouse gene. (J:260511)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1058 strains or lines available

References

• Original: J:260511 Wang P, et al., Generation of Mouse for Conditional Expression of Forkhead Box A2. Endocrinology. 2018 Apr 1;159(4):1897-1909
• All: 1 reference(s)