Dll1^em1.2Gos
Endonuclease-mediated Allele Detail

Summary

• Symbol: Dll1^em1.2Gos
• Name: delta like canonical Notch ligand 1; endonuclease-mediated mutation 1.2, Achim Gossler
• MGI ID: MGI:6781221
• Synonyms: Dll1^SF
• Gene: Dll1 Location: Chr17:15587616-15597134 bp, - strand Genetic Position: Chr17, 8.95 cM
• Alliance: Dll1^em1.2Gos page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Epitope tag)
• Mutation: Insertion
• Mutation details: CRISPR-targeting with a donor plasmid inserted into intron 10 a floxed monomeric AcGFP reporter gene with a fused in-frame HA tag and stop cassette, Strep/FLAG tag (SF), and FRT3-flanked puromycin resistance cassette. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed the reporter gene and HA tag. (J:311810)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Dll1 Mutation: 45 strains or lines available

References

• Original: J:311810 Schuster-Gossler K, et al., Activity of the mouse Notch ligand DLL1 is sensitive to C-terminal tagging in vivo. BMC Res Notes. 2021 Sep 28;14(1):383
• All: 1 reference(s)