Pik3c3^tm1Bvan
Targeted Allele Detail

Summary

• Symbol: Pik3c3^tm1Bvan
• Name: phosphatidylinositol 3-kinase catalytic subunit type 3; targeted mutation 1, Bart Vanhaesebroeck
• MGI ID: MGI:6780732
• Synonyms: Pik3c3^lox
• Gene: Pik3c3 Location: Chr18:30405800-30481179 bp, + strand Genetic Position: Chr18, 17.41 cM
• Alliance: Pik3c3^tm1Bvan page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:251923
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• The targeting construct floxed exon 21. (J:251923)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Pik3c3 Mutation: 48 strains or lines available

References

• Original: J:251923 Valet C, et al., A dual role for the class III PI3K, Vps34, in platelet production and thrombus growth. Blood. 2017 Nov 2;130(18):2032-2042
• All: 3 reference(s)