Clstn1^tm1.1Tymo
Targeted Allele Detail

Summary

• Symbol: Clstn1^tm1.1Tymo
• Name: calsyntenin 1; targeted mutation 1.1, Toru Yamamoto
• MGI ID: MGI:6780683
• Gene: Clstn1 Location: Chr4:149670925-149733356 bp, + strand Genetic Position: Chr4, 79.91 cM, cytoband E1
• Alliance: Clstn1^tm1.1Tymo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:297152
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct replaced exon 1 with a beta-geo reporter cassette and FRT-flanked neomycin resistance cassette. (J:297152)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Clstn1 Mutation: 56 strains or lines available

References

• Original: J:297152 Gotoh N, et al., Amyloidogenic processing of amyloid beta protein precursor (APP) is enhanced in the brains of alcadein alpha-deficient mice. J Biol Chem. 2020 Jul 10;295(28):9650-9662
• All: 3 reference(s)