Stmn2^em1Eggn
Endonuclease-mediated Allele Detail

Summary

• Symbol: Stmn2^em1Eggn
• Name: stathmin-like 2; endonuclease-mediated mutation 1, Kevin Eggan
• MGI ID: MGI:6780035
• Gene: Stmn2 Location: Chr3:8574587-8626664 bp, + strand Genetic Position: Chr3, 2.15 cM
• Alliance: Stmn2^em1Eggn page

Mutation origin

• Strain of Origin: C57BL/6NJ

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Guide RNAs (CGCAACATCAACATCTAC and AGCGAGAGGTGCTCCAGA) are designed to delete a 13 kb the region between exons 2 and 4. (J:339262)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Stmn2 Mutation: 42 strains or lines available

References

• Original: J:339262 Guerra San Juan I, et al., Loss of mouse Stmn2 function causes motor neuropathy. Neuron. 2022 May 18;110(10):1671-1688.e6
• All: 1 reference(s)