Otulin^em1Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Otulin^em1Gpt
• Name: OTU deubiquitinase with linear linkage specificity; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
• MGI ID: MGI:6780019
• Synonyms: Otulin^em1Cflox, Otulin^loxP
• Gene: Otulin Location: Chr15:27606005-27630793 bp, - strand Genetic Position: Chr15, 10.31 cM
• Alliance: Otulin^em1Gpt page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 2 through 7 were floxed. (J:308817)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Otulin Mutation: 22 strains or lines available

References

• Original: J:308817 Fu Y, et al., OTULIN allies with LUBAC to govern angiogenesis by editing ALK1 linear polyubiquitin. Mol Cell. 2021 Aug 5;81(15):3187-3204.e7
• All: 1 reference(s)