Pbk^em1Sdgl
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pbk^em1Sdgl
• Name: PDZ binding kinase; endonuclease-mediated mutation 1, Sandeep Goel
• MGI ID: MGI:6771577
• Gene: Pbk Location: Chr14:66043337-66055271 bp, + strand Genetic Position: Chr14, 34.36 cM
• Alliance: Pbk^em1Sdgl page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 3 generated a 5 bp deletion. (J:311405)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pbk Mutation: 37 strains or lines available

References

• Original: J:311405 Miki Y, et al., Deletion of the PDZ-binding kinase (Pbk) gene does not affect male fertility in mice. Reprod Fertil Dev. 2020 Jun;32(10):893-902
• All: 1 reference(s)