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Hmcn1tm1.1Hamm
Targeted Allele Detail
Summary
Symbol: Hmcn1tm1.1Hamm
Name: hemicentin 1; targeted mutation 1.1, Matthias Hammerschmidt
MGI ID: MGI:6765431
Gene: Hmcn1  Location: Chr1:150438275-150869186 bp, - strand  Genetic Position: Chr1, 63.84 cM
Alliance: Hmcn1tm1.1Hamm page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:310857
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsPart of exon 1 was replaced with an FRT flanked neo cassette via homologous recombination. Flp mediated recombination removed the neo cassette. (J:310857)
Expression
In Mice Carrying this Mutation: 10 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hmcn1 Mutation:  343 strains or lines available
References
Original:  J:310857 Welcker D, et al., Hemicentin-1 is an essential extracellular matrix component of the dermal-epidermal and myotendinous junctions. Sci Rep. 2021 Sep 9;11(1):17926
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory