Plxnb1^tm1.1Rkun
Targeted Allele Detail

Summary

• Symbol: Plxnb1^tm1.1Rkun
• Name: plexin B1; targeted mutation 1.1, Rohini Kuner
• MGI ID: MGI:6764485
• Synonyms: Plxnb1^fl
• Gene: Plxnb1 Location: Chr9:108924457-108948985 bp, + strand Genetic Position: Chr9, 59.63 cM
• Alliance: Plxnb1^tm1.1Rkun page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:121970
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A neo/TK selection cassette flanked by loxP sites was introduced into intron 11 and an additional loxP site was introduced into intron 17. The neo/TK selection cassette was removed via Cre-mediated recombination (J:121970)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Plxnb1 Mutation: 107 strains or lines available

References

• Original: J:121970 Deng S, et al., Plexin-B2, but not Plexin-B1, critically modulates neuronal migration and patterning of the developing nervous system in vivo. J Neurosci. 2007 Jun 6;27(23):6333-47
• All: 2 reference(s)