Pcdh19^em1Umri
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pcdh19^em1Umri
• Name: protocadherin 19; endonuclease-mediated mutation 1, Hisashi Umemori
• MGI ID: MGI:6763969
• Gene: Pcdh19 Location: ChrX:132483609-132589736 bp, - strand Genetic Position: ChrX, 55.21 cM
• Alliance: Pcdh19^em1Umri page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology generated a 3253 bp deletion, deleting the first exon. (J:310602)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pcdh19 Mutation: 8 strains or lines available

References

• Original: J:310602 Hoshina N, et al., Female-specific synaptic dysfunction and cognitive impairment in a mouse model of PCDH19 disorder. Science. 2021 Apr 16;372(6539)
• All: 1 reference(s)