Mydgf^tm1.1Smoc
Targeted Allele Detail

Summary

• Symbol: Mydgf^tm1.1Smoc
• Name: myeloid derived growth factor; targeted mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:6762188
• Gene: Mydgf Location: Chr17:56483541-56490920 bp, - strand Genetic Position: Chr17, 29.2 cM
• Alliance: Mydgf^tm1.1Smoc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:310335
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 1-3 were flanked by loxP sites. Exons 1-3 and the neomycin cassette were deleted via cre-mediated recombination in the germline. (J:310335)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mydgf Mutation: 16 strains or lines available

Notes

Currently, SMOC provides mouse ES cells with three types of genetic background: C57BL/6, 129/S6, B6;129

References

• Original: J:310335 Wang Y, et al., Mydgf promotes Cardiomyocyte proliferation and Neonatal Heart regeneration. Theranostics. 2020;10(20):9100-9112
• All: 1 reference(s)