Prdm16^tm1Kmori
Targeted Allele Detail

Summary

• Symbol: Prdm16^tm1Kmori
• Name: PR domain containing 16; targeted mutation 1, Kazuhiro Morishita
• MGI ID: MGI:6761837
• Synonyms: Mel1/Prdm16^-
• Gene: Prdm16 Location: Chr4:154400582-154721330 bp, - strand Genetic Position: Chr4, 83.96 cM, cytoband E2
• Alliance: Prdm16^tm1Kmori page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:318856
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: The targeting construct inserted a neomycin resistance cassette into exon 6 with the first methionine of the short-form MEL1/PRDM16. (J:104881, J:318856)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Prdm16 Mutation: 73 strains or lines available

References

• Original: J:318856 Kaneda-Nakashima K, et al., Role of Mel1/Prdm16 in bone differentiation and morphology. Exp Cell Res. 2022 Jan 15;410(2):112969
• All: 2 reference(s)