Cables2^em2Utr
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cables2^em2Utr
• Name: CDK5 and Abl enzyme substrate 2; endonuclease-mediated mutation 2, Ken-ichi Yagami
• MGI ID: MGI:6761760
• Synonyms: Cables2^e1
• Gene: Cables2 Location: Chr2:179900332-179915258 bp, - strand Genetic Position: Chr2, 102.78 cM
• Alliance: Cables2^em2Utr page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted exon 1. (J:309963)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cables2 Mutation: 13 strains or lines available

References

• Original: J:309963 Dinh TTH, et al., Disruption of entire Cables2 locus leads to embryonic lethality by diminished Rps21 gene expression and enhanced p53 pathway. Elife. 2021 May 5;10:e50346
• All: 1 reference(s)