Gt(ROSA)26Sortm2(Asxl1)Toki
Targeted Allele Detail
|
Symbol: |
Gt(ROSA)26Sortm2(Asxl1)Toki |
Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Toshio Kitamura |
MGI ID: |
MGI:6760603 |
Synonyms: |
Asxl1-MTfl, Gt(ROSA)26Sortm2(Asxl1<*)Toki> |
Gene: |
Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
|
Alliance: |
Gt(ROSA)26Sortm2(Asxl1)Toki page
|
|
|
Allele Type: |
|
Targeted (Conditional ready, Inserted expressed sequence, No functional change) |
Mutation: |
|
Insertion
|
|
|
Mutation details: The targeting construct inserted into the locus an adenovirus splicing acceptor), floxed neomycin resistance/stop cassette, N-terminal triple FLAG tag, mouse Asxl1 (1-1,890) cDNA with the point mutation, FRT sites, IRES, jellyfish EGFP reporter gene, and bovine growth hormone polyA.
(J:265682)
|
|
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
Carrying any Gt(ROSA)26Sor Mutation: |
945 strains or lines available
|
|
Original: |
J:265682 Nagase R, et al., Expression of mutant Asxl1 perturbs hematopoiesis and promotes susceptibility to leukemic transformation. J Exp Med. 2018 Jun 4;215(6):1729-1747 |
All: |
4 reference(s) |
|