Scd1^em1Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Scd1^em1Smoc
• Name: stearoyl-Coenzyme A desaturase 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:6760590
• Synonyms: Scd1^{em1(flox)Smoc}, Scd1^flox
• Gene: Scd1 Location: Chr19:44382889-44396148 bp, - strand Genetic Position: Chr19, 37.98 cM
• Alliance: Scd1^em1Smoc page

Mutation origin

• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• These mice carry loxP sites exon 3 of Scd1 gene. (J:238766, J:285348)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Scd1 Mutation: 23 strains or lines available

References

• Original: J:285348 Liu K, et al., Scd1 controls de novo beige fat biogenesis through succinate-dependent regulation of mitochondrial complex II. Proc Natl Acad Sci U S A. 2020 Feb 4;117(5):2462-2472
• All: 3 reference(s)